Mercredi 3 octobre 2012 3 03 /10 /Oct /2012 22:03
Vienne, le mercredi 3 octobre 2012 - Comme l’avait déjà suggéré une enquête de l’Institut national de prévention et d’éducation à la santé (INPES), une étude présentée cette semaine à Vienne au congrès de la société européenne d’oncologie médicale (ESMO) par le Docteur Derek Power (Irlande) confirme que le grand public a une perception souvent erronée des principaux facteurs de risque de cancer. Menée auprès de 748 personnes cette enquête invitait les sondés à se prononcer sur 48 items différents. Il apparaît ainsi que beaucoup sont convaincus de l’impact délétère des prothèses mammaires, du stress, du port de sous-vêtements serrés, de l’exposition aux ondes électromagnétiques et de l’utilisation des aérosols. Par ailleurs, « 15 % des gens interrogés croient que le risque de cancer lié au mode de vie n’est pas modifiable » signale Derek Power, tandis que le responsable de la prévention au sein de la Société européenne d’oncologie, le professeur Hans-Jörg Senn (Suisse) remarque : « Une grande proportion d'Européens n'apprécie pas particulièrement l'idée de la responsabilité individuelle dans la prévention du cancer, car cela sous-entend de changer ses habitudes et son mode de vie. Ils préfèrent donc blâmer la génétique ou la société ».
Par Chronimed - Publié dans : Nutrition
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Dimanche 30 septembre 2012 7 30 /09 /Sep /2012 20:57
Having the right bacteria present in a person's sinuses might be key to preventing chronic sinusitis, say researchers.
Reporting in Science Translational Medicine , the team found that the microbial communities present in the sinuses of people with chronic sinusitis and healthy controls differed significantly.
Sinusitis sufferers had a significantly greater proportion of Corynebacterium tuberculostearicum than controls. Conversely, healthy individuals appeared to have a greater number of Lactobacillus sakei than sinusitis patients, which appeared to convey a protective effect.
"Presumably these are sinus-protective species," commented study author Susan Lynch (University of California, San Francisco, USA) in a press statement.
Lynch and colleagues recruited 10 patients with chronic sinusitis and 10 healthy controls to assess the composition of their sinus microbial communities.
The researchers used comparative microbiome profiling to determine the species and proportions of bacteria present in the sinuses of the participants.
The chronic sinusitis patients had significantly reduced microbial diversity compared with the controls. In particular there was a notable decline in the numbers of multiple, phylogenetically distinct lactic acid bacteria and a notable increase in the abundance of C. tuberculostearicum .
Using a murine model, the researchers confirmed the pathogenic potential of C. tuberculostearicum and showed that L. sakei , which was present in significantly higher numbers in people without sinusitis, is able to defend against sinus infection with C. tuberculostearicum, even if other bacteria are depleted.
Sinusitis can be a difficult condition to treat, with antibiotics commonly prescribed and sometimes even surgery. However, co-author Andrew Goldberg, also from the University of California, commented "the premise for our understanding of chronic sinusitis and therapeutic treatment appears to be wrong, and a different therapeutic strategy seems appropriate."
Our results "demonstrate that sinus mucosal health is highly dependent on the composition of the resident microbiota as well as identify both a new sinopathogen and a strong bacterial candidate for therapeutic intervention," conclude the authors.
By Helen Albert, Senior medwireNews Reporter 21/09/2012
Par Chronimed - Publié dans : Nutrition
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Samedi 29 septembre 2012 6 29 /09 /Sep /2012 13:01
Du ginseng pour la fatigue liée à un cancer? Des résultats, mais pas immédiats La fatigue est l'une des manifestations les plus pénibles du cancer, quel qu'en soit le type. Pour tenter d'améliorer ce symptôme, une équipe américaine a testé un traitement en double aveugle par Ginseng 2000 mg/jour durant auprès de 364 patients. Résultat: aucun bénéfice à 4 semaines, mais une amélioration significative de tous les items du Multidimensional Fatigue Symptome Inventory à 8 semaines. Dr Dominique-Jean Bouilliez Barton D, et coll. Phase III evaluation of American ginseng (panax quinquefolius) to improve cancer-related fatigue: NCCTG trial N07C2. ASCO annual meeting. 1er au 5 juin 2012. Chicago (USA) Publié le 28/09/2012
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Samedi 29 septembre 2012 6 29 /09 /Sep /2012 12:33
Dr. Jonny Bowden. If you've ever struggled with weight gain, Jonny sheds some light on why that happens and the 5 "little demons" that seem to be out of your control that are conspiring to make you fat, particularly around your belly. Enjoy! Warmest regards, Daniel G. Amen, MD Founder, and Medical Director Amen Clinics, Inc. Article: Nobody smokes cigarettes because they didn’t get the memo about lung cancer. And nobody over-eats junk food because they didn’t get the memo about sugar. No, we continue to eat foods that pack on the belly fat not because we don’t know how bad those foods are, but because we can’t resist them – and that’s by design. You see, there are powerful forces that are seemingly outside of our control that conspire to not just make us fat, but also to make us sick, tired and even depressed. I call these forces the “little demons” and they wreak havoc on our ability to control our cravings, combat urges and avoid temptation and result in expanded waistlines, failed diets and drained energy. But there is a series of simple steps you can take to send these little demons scurrying, take back control of your life and your waistline. Let me explain. Little Demon #1: Addictive Food Big Food has learned how to layer their products with just the right, scientifically determined amounts of salt, fat and sugar to produce what they call “super-palatable” food – or what you and I would simple call “addictive”. Brain studies have shown that these foods are just as addictive as drugs, alcohol and gambling are. It’s no accident that “you can’t eat just one”. For example, your brain remembers the sensation of eating a CinnaBon; next time you smell one, your neurons secrete a brain chemical called dopamine which virtually insures that you won’t stop till you eat one. So next time you feel yourself being magnetically pulled to eat a particular food, just know that there is some mad food scientist smiling somewhere, eager to line his pockets at your expense, so turn the other way and don’t give him the satisfaction! Little Demon #2: Food Labeling Tricks Manufacturers have to list ingredients used in greatest amounts listed first. So when manufacturers don’t want you to know that the main ingredient is sugar, they deceive you by using a dozen different forms of sugar so they can list each one further down. Sneaky huh? For example, all of the following are sugar in disguise: agave nectar, barley malt syrup, dehydrated cane juice, dextrose, corn syrup, brown rice syrup, raw sugar, turbinado sugar, sucrose, maltodextrin. You can avoid succumbing to food labeling tricks by, well, avoiding foods that have labels in the first place! Shop around the perimeter of your grocery story and eat fresh, whole, real foods focusing on leafy green vegetables and grass-fed, pasture-raised or organic meats. Little Demon #3: The Troll in your Brain The reward pathways in our brains are powerful motivators, and they will trick your conscious mind every single time. Whenever you hear yourself saying, “Aw, just one won’t kill me”, “I just don’t have time to cook” or “I can start my diet tomorrow”, you can be sure that’s the big fat ugly “troll” in your brain, doing the bidding of your dopamine reward system. These voices can sabotage your willpower, but there is a way to turn the table: next time you hear this voice, think of it as coming from someone – or something else, like a troll. By externalizing this voice, you’ll then realize something “else” is trying to manipulate you and you can train yourself to ignore these voices. Little Demon #4: Chronic Stress Chronic stress may begin in your brain—but it ends up packing on packing on fat, especially around your belly. When you’re stressed, one way body responds is by churning out a big dose of cortisol. Cortisol “instructs” the body to preserve fat around the middle, stimulates insulin – the primary hormone responsible for storing the food you eat as fat – and it also breaks down muscle, slowing your metabolic rate and making fat storage certain. And cortisol sends a signal to the brain to “refuel” for an emergency, usually with foods highest in fat, salt and sugar. The result? You walk around stressed and starving and you’ll eat anything in sight, particularly the stuff that makes you fat and sick. Because it’s so hard to resist temptation when you are stressed, the #1 way to combat the effects of stress you can do is to take an inventory of your life, and figure out how to minimize stress as much as possible. Also consider doing some form of active relaxation, whether meditation, yoga, deep breathing or something similar. Little Demon #5: Cheap Food Available 24x7 The previous 4 little demons wouldn’t make much of a difference if the food that makes us fat and sick weren’t available. But it is. Everywhere. And that’s little demon #5. Hunting and gathering? Fooey. Just go to the nearest drive through or pick up the phone. The easiest way to combat this toxic food environment is to remove temptation from your immediate environment so it’s NOT convenient. For example, at home, get rid of all the sugary junk food that will tempt you when your defenses are down. If an urge comes, you’ll have created a practical barrier that’s large enough to give you enough time for that urge to pass. What to Do Next… These 5 little demons conspire to make us sick and fat – but that does NOT mean we are all doomed. Simply by reading this article and becoming aware of these little demons that silently influence you to get fat, you’ve taken the first step toward building a mental defense to withstand their assault. Yours truly, Jonny Bowden, PhD, CNS aka “the Rogue Nutritionist”™
Par Chronimed - Publié dans : Nutrition
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Vendredi 28 septembre 2012 5 28 /09 /Sep /2012 05:32
Gut bacteria to control obesity K. S. Jayaraman Indian scientists studying gut bacteria in lean and fat people report that the research may open up a "novel and natural way" of combating obesity1. © Macmillan South Africa The scientists, who studied the differences between the dominant gut microbiota of lean and obese Indians, discovered that certain bacterial groups are prominent in the obese in comparison to the lean. Since a large fraction of microbes inhabiting gut cannot be grown in the laboratory, they used methods based on the direct detection of their genetic material, DNA. These methods focus on a specific gene, called 16S rRNA gene present in all living organisms except viruses. They report, for the first time, an analysis and comparison of gut microbiota by sequencing 16S rRNA gene libraries. The study revealed that methane producing 'archaea' — a group of single-celled microorganisms genetically distinct from bacteria and often living in extreme environmental conditions — was one of the predominant organisms in the gut of obese people. The other major organisms in the obese were 'bacteroides', a genus of gram-negative, anaerobic, rod-shaped bacteria. Both are known to produce small chain fatty acids (SCFA) — specifically propionate and acetate. Acetate is known to increase adipose (fat) tissue in experimental animals. "The predominance of bacteroides and archea results in elevated glucose and SCFA supply resulting in obesity," Yogesh Shouche, the lead investigator at the National Centre for Cell Science in Pune told Nature India. "The phenomenon is reversed in lean individuals who have comparatively lower bacteroides and archaea." The researchers have identified a representative microbial diversity in Indians and demonstrated the prominence of certain bacterial groups in obese people. These studies are important in many ways, Shouche explains. "If one confirms the association of specific groups of microbes with leanness, then it opens up the possibility of having a novel, natural means of controlling obesity. Cultivating such microbes in the lab are especially important for this." Shouche admits that in order to establish a direct role of any bacteria in the pathogenesis or treatment of obesity, a much more in-depth study is required. "However, our work is a stepping stone in appreciation of obesity associated gut microbiota among Indians." A follow-up study2 threw a surprise when the researchers attempted the isolation of gut microflora. They noticed that more than 25% of the cultivated anaerobes — organisms that do not require oxygen for their growth — seemed to be new to science. This, Shouche said,"suggests that gut microflora in Indian population is under explored and is a good source for finding novel bacterial species." References Patil, D. P. et al. Molecular analysis of gut microbiota in obesity among Indian individuals. J. Biosci. 37, 647-657 (2012) | Article | PubMed | Marathe, N. et al. Changes in human gut flora with age: An Indian familial study. Biomed. Central (in press)
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